HCV-Ag │ Recombinant Hepatitis C Virus antigen

Product Description:

Hepatitis C is a viral disease caused by the hepatitis C virus (HCV), leading to inflammation of the liver. It is primarily transmitted through exposure to infectious blood, such as through sharing needles, accidental needle sticks, or contact with blood from an infected person. Most people with acute HCV infection are asymptomatic, but the infection can progress to a chronic state in 80% to 85% of cases, potentially leading to cirrhosis, liver failure, and hepatocellular carcinoma.

Recommended Applications:

Lateral flow immunoassay, ELISA

Recommended Pairing:

For application in double-antigen sandwich for capture, pair with MI00301 for detection.

Buffer System:

50mM Tris-HCl, 0.15M NaCl, pH 8.0

Resconstitution:

Please see Certificate of Analysis (COA) for which is sent along with the products.

Shipping:

Recombinant proteins in lyophilized powder form are transported at ambient temperature.

Storage:

For long term storage, the product is stable for up to two years by stored at -20℃ or lower.

Please use the product (liquid form or lyophilized powder after reconstitution) within 2 weeks if it is stored at 2-8℃.

Please avoid repeated freeze-thaw cycles.

Please contact us for any concerns.

Background:

Hepatitis C Virus (HCV) is spherical and less than 80nm in diameter (36-40nm in liver cells and 36-62nm in blood). It is a single plus-stranded RNA Virus surrounded by a lipid-like capsule with spikes on the nucleocapsid. The protective immunity produced after the human infection HCV is very poor, and can be re-infected, and even some patients can lead to liver cirrhosis and hepatocellular carcinoma. About half of the remaining patients are self-limited and can recover automatically.