HIV-gp36 │ Recombinant Human Immunodeficiency Virus2 (HIV-gp36) antigen
Product Description:
HIV, or human immunodeficiency virus, is a retrovirus that primarily targets cells of the human immune system, particularly CD4-positive T-cells, leading to their destruction or impairment. This progressive depletion of the immune system results in immunodeficiency, making individuals more susceptible to opportunistic infections and certain cancers. The virus is transmitted through contact with infected blood, semen, vaginal fluids, and breast milk, with sexual contact, sharing of needles, and from mother to child during childbirth being the primary modes of transmission.
Recommended Applications:
Lateral flow immunoassay, ELISA
Recommended Pairing:
For application in double-antigen sandwich for detection, pair with AI00515 for capture.
Buffer System:
50mM Tris-HCl, 0.15M NaCl, pH 8.0
Resconstitution:
Please see Certificate of Analysis (COA) for which is sent along with the products.
Shipping:
Recombinant proteins in liquid form are transported in frozen form with blue ice.
Storage:
For long term storage, the product is stable for up to two years by stored at -20℃ or lower.
Please use the product (liquid form or lyophilized powder after reconstitution) within 2 weeks if it is stored at 2-8℃.
Please avoid repeated freeze-thaw cycles.
Please contact us for any concerns.
Background:
Human Immunodeficiency Virus, there are four genotypes, M, N, O and P, and the main transmission is M and N which are about 120 nanometers in diameter and roughly spherical. The outer membrane of the virus is a lipid envelope containing the viral proteins GP120 and GP41. Gp41 is a transmembrane protein. Gp120 is located on the surface and binds to GP41 by non-covalent interaction. Inward are the spherical Matrix formed by protein P17 and the semi-conical Capsid formed by protein P24.