SARS-CoV-2 Neutralizing antibody Test Cassette

Product Description:

The SARS-CoV-2 Neutralizing antibody Test Cassette is a rapid chromatographic immunoassay for the qualitative detection of neutralizing antibody of Coronavirus Disease 2019 in human whole blood,serum,or plasma as an aid in the Evaluation levels of human anti-novel coronavirus neutralizing antibody titer. The genus γ mainly causes bird infections.CoV is mainly transmitted through direct contact with secretions or through aerosols and droplets. There is also evidence that it can be transmitted through the fecal-oral route.

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2, or 2019-nCoV) is an enveloped non-segmented positive-sense RNA virus. It is the cause of coronavirus disease 2019 (COVID-19), which is contagious in humans.

SARS-CoV-2 has several structural proteins including spike (S), envelope (E), membrane (M) and nucleocapsid (N). The spike protein (S) contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor, angiotensin converting enzyme-2 (ACE2). It is found that the RBD of the SARS-CoV-2 S protein strongly interacts with the human ACE2 receptor leading to endocytosis into the host cells of the deep lung and viral replication.

Infection with the SARS-CoV-2 initiates an immune response, which includes the production of antibodies in the blood. The secreted antibodies provide protection against future infections from viruses, because they remain in the circulatory system for months to years after infection and will bind quickly and strongly to the pathogen to block cellular infiltration and replication. These antibodies are named neutralizing antibodies.

Application:

The SARS-CoV-2 Neutralizing antibody Test Cassette is a rapid diagnostic tool designed to qualitatively detect neutralizing antibodies of the novel coronavirus in human whole blood, serum, or plasma, assisting in evaluating the levels of these antibodies in individuals. This test is crucial for monitoring the immune response to COVID-19, providing insight into the effectiveness of vaccines and natural immunity, and guiding public health strategies. It enables healthcare professionals to assess the population's immunity levels and inform vaccination campaigns, ensuring targeted interventions and better resource allocation.

Storage: 4-30°C

Executive Standards: International Standard.