HCV - Mas │ Mouse Anti - Hepatitis C faylka fayraska monoclonal-ka antibodyl

Sharraxaadda Wax soo saarka:

Cagaarshowga C waa cudur fayras keena ee ay keento fayraska cagaarshowga C (HCV), taasoo horseedaysa in la soo baxo bararka beerka. Waxaa ugu horreyn lagu kala qaadaa soo-gaadhista dhiigga faafa, sida iyada oo loo marayo wadaagida cirbadaha, ulaha irbadda shilka ah, ama taabashada dhiigga qof cudurka qaba. Inta badan dadka qaba infakshanka HCV ee ba'an waa asymptomatic, laakiin infekshanku wuxuu u gudbin karaa dowlad dabadheeraad ah 80% illaa 85% kiisaska, oo horseedi kara cirroshosis, beerka oo ku dhaca beerka, iyo buugga maskaxda.

Dabeecadda molikalularL:

Antibsody-ka Monoclonal-ka wuxuu leeyahay xisaabtanka MW oo 160 KDA ah.

Codsiyada lagu taliyay:

Qulqulka dambe ee Ivansassay, Elisa

Lammaanaha lagu taliyay:

Codsiga labanlaab ah - antibordy rooti oo lagu ogaanayo, lammaane la00301 oo qabashada.

Nidaamka Buffer:

0.01m PBS, Ph7.4

Soomaaliya:

Fadlan ka eeg Shahaadada Falanqaynta (COA) ee loo diro alaabada.

Maraakiibta:

Borotiinnada dib-u-celinta ee foomka dareeraha ah waxaa lagu qaadaa foomka qabow ee baraf buluug ah.

Bakhaar:

Kaydinta muddada dheer, sheyga waa mid deggan ilaa labo sano iyadoo lagu keydiyo AT - 20 ℃ ama ka hooseeya.

Fadlan isticmaal sheyga (foomka dareeraha) 2 toddobaad gudahood haddii lagu keydiyo 2 - 8 ℃.

Fadlan iska ilaali qaboojiyaha soo noqnoqda - wareegga tuubada.

Fadlan nala soo xiriir wixii walaac ah.

Aasaas:

Cagaarshowga C (HCV) waa mid ka yar 100nm dhexroor (36 - 40 kunm oo ku dhex yaal unugyada beerka iyo 36 - 62m dhiig). Waa hal lagu daray oo lagu daray - fayraska xayiran ee xarkaha ah ee ay ku hareereysan yihiin lipid - sida kaabsoor leh oo ku yaal daaqadaha ku yaal nucleocapid. Daaweynta difaaca ee la soo saaray ka dib HCV-ga bini-aadamka ayaa aad u liita, waana dib u noqon karaa in la dhajiyo - cudurka, iyo xitaa bukaannada qaar waxay u horseedi karaan ciirrosis beerka iyo kan hepatocellular carcinoma. Qiyaastii kalabar bukaannada haray waa nafta - xadidan oo si otomaatig ah uga soo kabsan kara.